Chloroethylclonidine: an irreversible agonist at prejunctional α2-adrenoceptors in rat vas deferens
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منابع مشابه
Prejunctional and postjunctional actions of heptanol and 18β-glycyrretinic acid in the rodent vas deferens
Heptanol and 18 beta-glycyrrhetinic acid (18 beta GA) block gap junctions, but have other actions on transmitter release that have not been characterised. This study investigates the prejunctional and postjunctional effects of these compounds in guinea pig and mouse vas deferens using intracellular electrophysiological recording and confocal Ca(2+) imaging of sympathetic nerve terminals. In mic...
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The relaxatory effect of Vitis vinifera leaf extract on rat uterus has been reported and it was postulated that, the extract relaxed through the blockade of voltage dependent calcium channels. The extract also, relaxed rat aorta through NO and was dependent on the functional endothelium. In the present study, the effect of Vitis vinifera hydroalcoholic leaf extract (VHLE) on rat vas deferens pr...
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Regulation of the supersensitivity and subsensitivity of the alpha adrenergic (alpha-Ad) system of rat vas deferens cultured under various experimental conditions was investigated. Muscles cultured for 3 days in normal medium (Eagle's MEM) exhibited marked increase in maximal contraction to noradrenaline (NA) and high K+ (154 mM), while muscles cultured with NA (100 microM) were subsensitive to...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1993
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1993.tb12806.x